SMARCA1
Summary: This gene encodes a member of the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription. The protein may also play a role in DNA damage, growth inhibition and apoptosis of cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
NameSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 OMIM IDMIM:300012 Ensembl IDEnsembl:ENSG00000102038 HGNC IDHGNC:HGNC:11097 PHARMGKB IDPA35947 Map LocationXq25-q26.1 | |||||
Gene Categories:
TRANSCRIPTION FACTOR BINDINGGO terms in SMARCA1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0016589 | NURF complex |
| CC | IDA | GO:0043231 | intracellular membrane-bounded organelle |
| CC | IDA | GO:0090537 | CERF complex |
| BP | IEA | GO:0000733 | DNA strand renaturation |
Gene expression in normal tissue: SMARCA1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SMARCA1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2882 | Nuclear Receptors Meta-Pathway |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SMARCA1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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