iGMDRD908

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Standard Name
Drug Status
Drug Type
Standard NameEZH2 inhibitor in RAS wt
Drug StatusFamily
Drug Typeundefined

Drug-model tissue-cancer distribution: Bubble Plot

OTHEtissue: OTHE cancer: OTHER model num: 0OTHERtissue: OTHER cancer: Cancer of Unknown Primary (CUP) model num: 3

Drug-gene pathway enrichments

2reactome: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known2reactome: Generic Transcription Pathway2kegg: Hepatocellular carcinoma - Homo sapiens (human)2reactome: Gene expression (Transcription)2reactome: Transcriptional regulation by RUNX12reactome: RMTs methylate histone arginines2reactome: RNA Polymerase II Transcription2reactome: Chromatin modifying enzymes2reactome: Chromatin organization1wikipathways: Pathways Affected in Adenoid Cystic Carcinoma

Drug-gene GO enrichments

4MF: DNA binding3BP: chromatin remodeling3BP: transcription, DNA-templated3MF: protein binding3BP: ATP-dependent chromatin remodeling3CC: nucleoplasm2CC: RSC-type complex2BP: positive regulation of transcription, DNA-templated2CC: nucleus2BP: regulation of transcription by RNA polymerase II

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
8289 ARID1A 1
6594 SMARCA1 1
55193 PBRM1 1
Showing 1 to 3 of 3 rows

Gene in drug-gene network: Network Plot

Models in EZH2 inhibitor in RAS wt

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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