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TBX15

Summary: This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.[provided by RefSeq, Oct 2009].

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Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
NameT-box 15 OMIM IDMIM:604127 Ensembl IDEnsembl:ENSG00000092607 HGNC IDHGNC:HGNC:11594 PHARMGKB IDPA36357 Map Location1p12

GO terms in TBX15

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Term Type	Evidence Type	GO Term ID	GO Des.
MF	IEA	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
MF	ISA	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF	ISM	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF	IEA	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
MF	IEA	GO:0003714	transcription corepressor activity
MF	IPI	GO:0005515	protein binding

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Gene expression in normal tissue: TBX15

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TBX15

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Database	Pathway ID	Pathway Des.
No matching records found

Gene-Drug: Aster Plot

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Drug ID	Drug Name	Model Num.
iGMDRD284	Palbociclib	1

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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TBX15

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	Model	Level	Reference ID	Tissue	Cancer	Drug	Clinical Response	Source
No matching records found

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