SLC30A2


Summary: The protein encoded by this gene is a zinc transporter that acts as a homodimer. The encoded protein plays a role in secreting zinc into breast milk. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
solute carrier family 30 member 2MIM:609617Ensembl:ENSG00000158014HGNC:HGNC:11013PA358831p36.11

Gene Categories:

TRANSPORTER

GO terms in SLC30A2


Term TypeEvidence TypeGO Term IDGO Des.
BPIBAGO:0010043response to zinc ion
BPIBAGO:0061088regulation of sequestering of zinc ion
BPIDAGO:0061090positive regulation of sequestering of zinc ion
BPIBAGO:0071577zinc ion transmembrane transport
BPIEAGO:0071577zinc ion transmembrane transport
CCIDAGO:0005737cytoplasm
CCHDAGO:0005765lysosomal membrane
CCIDAGO:0005770late endosome
CCIBAGO:0005886plasma membrane
CCIBAGO:0016020membrane
CCIEAGO:0016021integral component of membrane
CCIDAGO:0043231intracellular membrane-bounded organelle
MFIBAGO:0005385zinc ion transmembrane transporter activity
MFIPIGO:0005515protein binding

Gene expression in normal tissue: SLC30A2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SLC30A2


DatabasePathway IDPathway Des.
reactomeR-HSA-382551Transport of small molecules
reactomeR-HSA-425366Transport of bile salts and organic acids, metal ions and amine compounds
reactomeR-HSA-425407SLC-mediated transmembrane transport
reactomeR-HSA-425410Metal ion SLC transporters
reactomeR-HSA-435354Zinc transporters
reactomeR-HSA-435368Zinc efflux and compartmentalization by the SLC30 family
wikipathwaysWP3529Zinc homeostasis

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD284Palbociclib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SLC30A2

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