OR13A1


Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
olfactory receptor family 13 subfamily A member 1Ensembl:ENSG00000256574HGNC:HGNC:14772PA3203010q11.21

GO terms in OR13A1


Term TypeEvidence TypeGO Term IDGO Des.
CCTASGO:0005886plasma membrane
CCIEAGO:0016021integral component of membrane
BPIBAGO:0007186G-protein coupled receptor signaling pathway
BPIBAGO:0007608sensory perception of smell
BPIEAGO:0050911detection of chemical stimulus involved in sensory perception of smell
MFIEAGO:0004930G-protein coupled receptor activity
MFIBAGO:0004984olfactory receptor activity
MFIBAGO:0005549odorant binding

Gene expression in normal tissue: OR13A1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in OR13A1


DatabasePathway IDPathway Des.
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-372790Signaling by GPCR
reactomeR-HSA-381753Olfactory Signaling Pathway
reactomeR-HSA-388396GPCR downstream signalling
reactomeR-HSA-418555G alpha (s) signalling events
kegghsa04740Olfactory transduction - Homo sapiens (human)
wikipathwaysWP3608Olfactory receptor activity

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012
iGMDRD30917AAG1
iGMDRD748PHA-6657521

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in OR13A1

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