GCC1
Summary: The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq, Jul 2008].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
GRIP and coiled-coil domain containing 1 | MIM:607418 | Ensembl:ENSG00000179562 | HGNC:HGNC:19095 | PA38796 | 7q32.1 |
GO terms in GCC1
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | IEA | GO:0000139 | Golgi membrane |
CC | IBA | GO:0005794 | Golgi apparatus |
CC | IDA | GO:0005794 | Golgi apparatus |
CC | IDA | GO:0005829 | cytosol |
CC | TAS | GO:0005829 | cytosol |
CC | IDA | GO:0005886 | plasma membrane |
MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: GCC1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GCC1
Database | Pathway ID | Pathway Des. |
---|---|---|
wikipathways | WP2882 | Nuclear Receptors Meta-Pathway |
reactome | R-HSA-199991 | Membrane Trafficking |
reactome | R-HSA-5653656 | Vesicle-mediated transport |
reactome | R-HSA-6811440 | Retrograde transport at the Trans-Golgi-Network |
reactome | R-HSA-6811442 | Intra-Golgi and retrograde Golgi-to-ER traffic |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GCC1