PGBD5


Summary: The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. [provided by RefSeq, May 2010].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in PGBD5


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0032196 transposition
BP IEA GO:0090305 nucleic acid phosphodiester bond hydrolysis
CC IEA GO:0005634 nucleus
MF IEA GO:0004519 endonuclease activity
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Gene expression in normal tissue: PGBD5

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PGBD5


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Database
Pathway ID
Pathway Des.
wikipathways WP4018 Pathways in clear cell renal cell carcinoma
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD284 Palbociclib 1
iGMDRD309 17AAG 1
iGMDRD68 Paclitaxel 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PGBD5

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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