ELMO3


Summary: The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in ELMO3


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IEA GO:0005737 cytoplasm
BP IEA GO:0006909 phagocytosis
BP IEA GO:0006915 apoptotic process
BP IEA GO:0016477 cell migration
MF IPI GO:0005515 protein binding
MF IEA GO:0017124 SH3 domain binding
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Gene expression in normal tissue: ELMO3

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in ELMO3


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Database
Pathway ID
Pathway Des.
kegg hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human)
kegg hsa05131 Shigellosis - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD399 Selumetinib 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ELMO3

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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