ELMO3
Summary: The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| engulfment and cell motility 3 | MIM:606422 | Ensembl:ENSG00000102890 | HGNC:HGNC:17289 | PA27756 | 16q22.1 |
GO terms in ELMO3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0005737 | cytoplasm |
| BP | IEA | GO:0006909 | phagocytosis |
| BP | IEA | GO:0006915 | apoptotic process |
| BP | IEA | GO:0016477 | cell migration |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0017124 | SH3 domain binding |
Gene expression in normal tissue: ELMO3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ELMO3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa05100 | Bacterial invasion of epithelial cells - Homo sapiens (human) |
| kegg | hsa05131 | Shigellosis - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ELMO3
CLASSFICATION
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