ELL3
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| elongation factor for RNA polymerase II 3 | MIM:609885 | Ensembl:ENSG00000128886 | HGNC:HGNC:23113 | PA128394728 | 15q15.3 |
GO terms in ELL3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | ISS | GO:0035326 | enhancer binding |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005730 | nucleolus |
| CC | IDA | GO:0008023 | transcription elongation factor complex |
| CC | NAS | GO:0008023 | transcription elongation factor complex |
| BP | IDA | GO:0006354 | DNA-templated transcription, elongation |
| BP | ISS | GO:0006366 | transcription by RNA polymerase II |
| BP | IDA | GO:0006368 | transcription elongation from RNA polymerase II promoter |
| BP | NAS | GO:0007283 | spermatogenesis |
| BP | ISS | GO:0010717 | regulation of epithelial to mesenchymal transition |
| BP | IDA | GO:0032786 | positive regulation of DNA-templated transcription, elongation |
| BP | IMP | GO:0042795 | snRNA transcription by RNA polymerase II |
| BP | TAS | GO:0042795 | snRNA transcription by RNA polymerase II |
| BP | IDA | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| BP | ISS | GO:0048863 | stem cell differentiation |
| BP | IEA | GO:0050769 | positive regulation of neurogenesis |
| BP | IEA | GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator |
| BP | IEA | GO:2000179 | positive regulation of neural precursor cell proliferation |
Gene expression in normal tissue: ELL3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ELL3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-6807505 | RNA polymerase II transcribes snRNA genes |
| reactome | R-HSA-6807505 | RNA polymerase II transcribes snRNA genes |
| reactome | R-HSA-73857 | RNA Polymerase II Transcription |
| reactome | R-HSA-73857 | RNA Polymerase II Transcription |
| reactome | R-HSA-74160 | Gene expression (Transcription) |
| reactome | R-HSA-74160 | Gene expression (Transcription) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ELL3
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.