SCUBE1

Summary: This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology. [provided by RefSeq, Oct 2011].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namesignal peptide, CUB domain and EGF like domain containing 1
OMIM IDMIM:611746
Ensembl IDEnsembl:ENSG00000159307
HGNC IDHGNC:HGNC:13441
PHARMGKB IDPA35019
Map Location22q13.2

GO terms in SCUBE1


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Term Type
Evidence Type
GO Term ID
GO Des.
MF TAS GO:0005509 calcium ion binding
MF IDA GO:0042802 identical protein binding
MF IDA GO:0046982 protein heterodimerization activity
CC IBA GO:0005615 extracellular space
CC IDA GO:0005615 extracellular space
CC TAS GO:0005886 plasma membrane
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Gene expression in normal tissue: SCUBE1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Cell cycle1

Pathways in SCUBE1


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1474228 Degradation of the extracellular matrix
reactome R-HSA-1474244 Extracellular matrix organization
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD284 Palbociclib 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SCUBE1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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