RAB34


Summary: This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. An alternatively spliced transcript variant produces the nine-amino acid residue-repeats (NARR) protein, which is a functionally distinct nucleolar protein resulting from a different reading frame. [provided by RefSeq, Dec 2016].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in RAB34


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0003924 GTPase activity
MF IEA GO:0003924 GTPase activity
MF IPI GO:0005515 protein binding
MF IEA GO:0005525 GTP binding
MF IPI GO:0017160 Ral GTPase binding
MF IPI GO:0030742 GTP-dependent protein binding
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Gene expression in normal tissue: RAB34

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RAB34


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Database
Pathway ID
Pathway Des.
wikipathways WP2002 miR-targeted genes in epithelium - TarBase
wikipathways WP2003 miR-targeted genes in leukocytes - TarBase
wikipathways WP2004 miR-targeted genes in lymphocytes - TarBase
wikipathways WP2005 miR-targeted genes in muscle cell - TarBase
wikipathways WP2006 miR-targeted genes in squamous cell - TarBase
reactome R-HSA-392499 Metabolism of proteins
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD134 Sorafenib 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RAB34

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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