BRMS1L


Summary: The protein encoded by this gene shows sequence similarity to the human breast carcinoma metastasis suppressor (BRMS1) protein and the mammalian Sds3 (suppressor of defective silencing 3) proteins. This protein is a component of the mSin3a family of histone deacetylase complexes (HDAC). [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
BRMS1 like transcriptional repressorEnsembl:ENSG00000100916HGNC:HGNC:20512PA13496835614q13.2

Gene Categories:

HISTONE MODIFICATION

GO terms in BRMS1L


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0004407histone deacetylase activity
MFIPIGO:0005515protein binding
MFIBAGO:0042826histone deacetylase binding
BPIBAGO:0000122negative regulation of transcription by RNA polymerase II
BPIEAGO:0006351transcription, DNA-templated
BPIBAGO:0016575histone deacetylation
BPIEAGO:0040008regulation of growth
CCIBAGO:0070822Sin3-type complex

Gene expression in normal tissue: BRMS1L

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in BRMS1L


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD190Nilotinib2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in BRMS1L

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