BRMS1L


Summary: The protein encoded by this gene shows sequence similarity to the human breast carcinoma metastasis suppressor (BRMS1) protein and the mammalian Sds3 (suppressor of defective silencing 3) proteins. This protein is a component of the mSin3a family of histone deacetylase complexes (HDAC). [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
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Gene Categories:

HISTONE MODIFICATION

GO terms in BRMS1L


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0004407 histone deacetylase activity
MF IPI GO:0005515 protein binding
MF IBA GO:0042826 histone deacetylase binding
BP IBA GO:0000122 negative regulation of transcription by RNA polymerase II
BP IEA GO:0006351 transcription, DNA-templated
BP IBA GO:0016575 histone deacetylation
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Gene expression in normal tissue: BRMS1L

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

ABL signaling1

Pathways in BRMS1L


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD190 Nilotinib 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in BRMS1L

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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