RAB11FIP4

Summary: The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of the encoded protein and enhance the metastatic potential of hepatocellular carcinoma. [provided by RefSeq, Oct 2016].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameRAB11 family interacting protein 4
OMIM IDMIM:611999
Ensembl IDEnsembl:ENSG00000131242
HGNC IDHGNC:HGNC:30267
PHARMGKB IDPA134978007
Map Location17q11.2

GO terms in RAB11FIP4


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0005509 calcium ion binding
MF IPI GO:0005515 protein binding
MF IBA GO:0017137 Rab GTPase binding
MF IPI GO:0017137 Rab GTPase binding
MF IBA GO:0030306 ADP-ribosylation factor binding
MF IPI GO:0030306 ADP-ribosylation factor binding
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Gene expression in normal tissue: RAB11FIP4

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

Protein stability and degradation1Cell cycle1

Pathways in RAB11FIP4


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Database
Pathway ID
Pathway Des.
kegg hsa04144 Endocytosis - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD284 Palbociclib 1
iGMDRD309 17AAG 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RAB11FIP4

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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