SEC16B
Summary: SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007 [PubMed 17192411]).[supplied by OMIM, Jun 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| SEC16 homolog B, endoplasmic reticulum export factor | MIM:612855 | Ensembl:ENSG00000120341 | HGNC:HGNC:30301 | PA162402680 | 1q25.2 |
GO terms in SEC16B
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0000139 | Golgi membrane |
| CC | IEA | GO:0005789 | endoplasmic reticulum membrane |
| CC | TAS | GO:0005829 | cytosol |
| CC | IBA | GO:0012507 | ER to Golgi transport vesicle membrane |
| CC | IDA | GO:0043231 | intracellular membrane-bounded organelle |
| CC | IBA | GO:0070971 | endoplasmic reticulum exit site |
| BP | IBA | GO:0007029 | endoplasmic reticulum organization |
| BP | IDA | GO:0007029 | endoplasmic reticulum organization |
| BP | IBA | GO:0007030 | Golgi organization |
| BP | IDA | GO:0007031 | peroxisome organization |
| BP | IMP | GO:0010628 | positive regulation of gene expression |
| BP | IEA | GO:0015031 | protein transport |
| BP | IMP | GO:0016559 | peroxisome fission |
| BP | IBA | GO:0048208 | COPII vesicle coating |
| BP | TAS | GO:0048208 | COPII vesicle coating |
| BP | IBA | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum |
| BP | IMP | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum |
| BP | IBA | GO:0070973 | protein localization to endoplasmic reticulum exit site |
Gene expression in normal tissue: SEC16B
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SEC16B
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-199977 | ER to Golgi Anterograde Transport |
| reactome | R-HSA-199991 | Membrane Trafficking |
| reactome | R-HSA-204005 | COPII-mediated vesicle transport |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-446203 | Asparagine N-linked glycosylation |
| reactome | R-HSA-5653656 | Vesicle-mediated transport |
| reactome | R-HSA-597592 | Post-translational protein modification |
| reactome | R-HSA-948021 | Transport to the Golgi and subsequent modification |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SEC16B
CLASSFICATION
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