SLFN11


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
schlafen family member 11MIM:614953Ensembl:ENSG00000172716HGNC:HGNC:26633PA14459635817q12

Gene Categories:

TUMOR SUPPRESSOR

GO terms in SLFN11


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0000049tRNA binding
MFIDAGO:0000049tRNA binding
MFIEAGO:0004386helicase activity
MFIPIGO:0005515protein binding
MFIEAGO:0005524ATP binding
MFIDAGO:0016887ATPase activity
CCIDAGO:0005634nucleus
CCIDAGO:0005654nucleoplasm
CCIDAGO:0005829cytosol
CCIDAGO:0016235aggresome
CCIDAGO:0090734site of DNA damage
BPIDAGO:0006974cellular response to DNA damage stimulus
BPIDAGO:0008156negative regulation of DNA replication
BPIDAGO:0010942positive regulation of cell death
BPIDAGO:0043111replication fork arrest
BPIBAGO:0051607defense response to virus
BPIMPGO:0051607defense response to virus
BPIMPGO:2000134negative regulation of G1/S transition of mitotic cell cycle

Gene expression in normal tissue: SLFN11

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SLFN11


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD103SN-381

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SLFN11

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