SPECC1
Summary: The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| sperm antigen with calponin homology and coiled-coil domains 1 | MIM:608793 | Ensembl:ENSG00000128487 | HGNC:HGNC:30615 | PA164718712 | 17p11.2 |
GO terms in SPECC1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0030036 | actin cytoskeleton organization |
| CC | IEA | GO:0005634 | nucleus |
| CC | IBA | GO:0005815 | microtubule organizing center |
| CC | IEA | GO:0016020 | membrane |
| CC | IBA | GO:0031941 | filamentous actin |
Gene expression in normal tissue: SPECC1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SPECC1
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SPECC1
CLASSFICATION
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