DMKN
Summary: This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Namedermokine OMIM IDMIM:617211 Ensembl IDEnsembl:ENSG00000161249 HGNC IDHGNC:HGNC:25063 PHARMGKB IDPA145149020 Map Location19q13.12 | |||||
Gene Categories:
DRUGGABLE GENOMEGO terms in DMKN
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| BP | IBA | GO:1903575 | cornified envelope assembly |
| BP | IEA | GO:1903575 | cornified envelope assembly |
| CC | IEA | GO:0005576 | extracellular region |
| CC | IBA | GO:0005615 | extracellular space |
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Gene expression in normal tissue: DMKN
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DMKN
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD131 | Erlotinib | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in DMKN
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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