RAB9A
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| RAB9A, member RAS oncogene family | MIM:300284 | Ensembl:ENSG00000123595 | HGNC:HGNC:9792 | PA34152 | Xp22.2 |
Gene Categories:
DRUGGABLE GENOMEGO terms in RAB9A
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005764 | lysosome |
| CC | IDA | GO:0005770 | late endosome |
| CC | IEA | GO:0005789 | endoplasmic reticulum membrane |
| CC | TAS | GO:0005829 | cytosol |
| CC | IEA | GO:0005886 | plasma membrane |
| CC | IBA | GO:0012505 | endomembrane system |
| CC | TAS | GO:0030133 | transport vesicle |
| CC | IBA | GO:0030139 | endocytic vesicle |
| CC | IEA | GO:0030670 | phagocytic vesicle membrane |
| CC | TAS | GO:0032588 | trans-Golgi network membrane |
| CC | ISS | GO:0042470 | melanosome |
| CC | IDA | GO:0045335 | phagocytic vesicle |
| CC | HDA | GO:0070062 | extracellular exosome |
| BP | IBA | GO:0006886 | intracellular protein transport |
| BP | IEA | GO:0015031 | protein transport |
| BP | IBA | GO:0032482 | Rab protein signal transduction |
| BP | IMP | GO:0032880 | regulation of protein localization |
| BP | IBA | GO:0042147 | retrograde transport, endosome to Golgi |
| BP | IMP | GO:0045921 | positive regulation of exocytosis |
| BP | IMP | GO:0052405 | negative regulation by host of symbiont molecular function |
| MF | IBA | GO:0003924 | GTPase activity |
| MF | IDA | GO:0003924 | GTPase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0005525 | GTP binding |
| MF | IDA | GO:0019003 | GDP binding |
| MF | IEA | GO:0042802 | identical protein binding |
Gene expression in normal tissue: RAB9A
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RAB9A
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-199991 | Membrane Trafficking |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-5653656 | Vesicle-mediated transport |
| reactome | R-HSA-597592 | Post-translational protein modification |
| reactome | R-HSA-6811440 | Retrograde transport at the Trans-Golgi-Network |
| reactome | R-HSA-6811442 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| reactome | R-HSA-8873719 | RAB geranylgeranylation |
| reactome | R-HSA-8876198 | RAB GEFs exchange GTP for GDP on RABs |
| reactome | R-HSA-9007101 | Rab regulation of trafficking |
| kegg | hsa05162 | Measles - Homo sapiens (human) |
| wikipathways | WP4180 | Ebola Virus Pathway on Host |
| wikipathways | WP4217 | Ebola Virus Pathway on Host |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RAB9A
CLASSFICATION
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