ANXA11
Summary: This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, Dec 2015].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| annexin A11 | MIM:602572 | Ensembl:ENSG00000122359 | HGNC:HGNC:535 | PA24825 | 10q22.3 |
GO terms in ANXA11
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0003723 | RNA binding |
| MF | IEA | GO:0005509 | calcium ion binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005544 | calcium-dependent phospholipid binding |
| MF | IEA | GO:0008429 | phosphatidylethanolamine binding |
| MF | HDA | GO:0023026 | MHC class II protein complex binding |
| MF | IPI | GO:0044548 | S100 protein binding |
| MF | IPI | GO:0048306 | calcium-dependent protein binding |
| BP | IEP | GO:0006909 | phagocytosis |
| BP | IMP | GO:0032506 | cytokinetic process |
| BP | IDA | GO:0051592 | response to calcium ion |
| CC | IDA | GO:0005635 | nuclear envelope |
| CC | NAS | GO:0005635 | nuclear envelope |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | NAS | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005819 | spindle |
| CC | IDA | GO:0005829 | cytosol |
| CC | HDA | GO:0016020 | membrane |
| CC | IDA | GO:0030496 | midbody |
| CC | IEA | GO:0042470 | melanosome |
| CC | IDA | GO:0042581 | specific granule |
| CC | IDA | GO:0042582 | azurophil granule |
| CC | IDA | GO:0045335 | phagocytic vesicle |
| CC | HDA | GO:0070062 | extracellular exosome |
Gene expression in normal tissue: ANXA11
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ANXA11
CLASSFICATION
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