BPIFB1


Summary: The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
BPI fold containing family B member 1Ensembl:ENSG00000125999HGNC:HGNC:16108PA2565420q11.21

Gene Categories:

DRUGGABLE GENOME

GO terms in BPIFB1


Term TypeEvidence TypeGO Term IDGO Des.
CCIDAGO:0005576extracellular region
CCTASGO:0005576extracellular region
CCHDAGO:0070062extracellular exosome
BPIDAGO:0002227innate immune response in mucosa
BPTASGO:0019730antimicrobial humoral response
BPIDAGO:0034144negative regulation of toll-like receptor 4 signaling pathway
MFNDGO:0003674molecular_function
MFIEAGO:0008289lipid binding

Gene expression in normal tissue: BPIFB1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in BPIFB1


DatabasePathway IDPathway Des.
reactomeR-HSA-168249Innate Immune System
reactomeR-HSA-168256Immune System
reactomeR-HSA-6803157Antimicrobial peptides

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD133Lapatinib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in BPIFB1

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