BPIFB1


Summary: The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20. [provided by RefSeq, Jul 2008].

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OMIM ID
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Gene Categories:

DRUGGABLE GENOME

GO terms in BPIFB1


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IDA GO:0005576 extracellular region
CC TAS GO:0005576 extracellular region
CC HDA GO:0070062 extracellular exosome
BP IDA GO:0002227 innate immune response in mucosa
BP TAS GO:0019730 antimicrobial humoral response
BP IDA GO:0034144 negative regulation of toll-like receptor 4 signaling pathway
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Gene expression in normal tissue: BPIFB1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in BPIFB1


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Database
Pathway ID
Pathway Des.
reactome R-HSA-168249 Innate Immune System
reactome R-HSA-168256 Immune System
reactome R-HSA-6803157 Antimicrobial peptides
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD133 Lapatinib 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in BPIFB1

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Model
Level
Reference ID
Tissue
Cancer
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Clinical Response
Source
No matching records found

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