BRMS1L
Summary: The protein encoded by this gene shows sequence similarity to the human breast carcinoma metastasis suppressor (BRMS1) protein and the mammalian Sds3 (suppressor of defective silencing 3) proteins. This protein is a component of the mSin3a family of histone deacetylase complexes (HDAC). [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| BRMS1 like transcriptional repressor | Ensembl:ENSG00000100916 | HGNC:HGNC:20512 | PA134968356 | 14q13.2 |
Gene Categories:
HISTONE MODIFICATIONGO terms in BRMS1L
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0004407 | histone deacetylase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0042826 | histone deacetylase binding |
| BP | IBA | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IBA | GO:0016575 | histone deacetylation |
| BP | IEA | GO:0040008 | regulation of growth |
| CC | IBA | GO:0070822 | Sin3-type complex |
Gene expression in normal tissue: BRMS1L
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in BRMS1L
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in BRMS1L
CLASSFICATION
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