CADPS


Summary: This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
calcium dependent secretion activatorMIM:604667Ensembl:ENSG00000163618HGNC:HGNC:1426PA260243p14.2

GO terms in CADPS


Term TypeEvidence TypeGO Term IDGO Des.
BPTASGO:0006887exocytosis
BPIEAGO:0015031protein transport
BPIEAGO:0016050vesicle organization
BPIEAGO:0016082synaptic vesicle priming
BPIEAGO:0050432catecholamine secretion
BPIEAGO:0099525presynaptic dense core vesicle exocytosis
CCTASGO:0005829cytosol
CCIEAGO:0030054cell junction
CCIEAGO:0030659cytoplasmic vesicle membrane
CCIEAGO:0098793presynapse
MFIPIGO:0005515protein binding
MFIEAGO:0008289lipid binding
MFISSGO:0019901protein kinase binding
MFIEAGO:0046872metal ion binding

Gene expression in normal tissue: CADPS

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CADPS


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD399Selumetinib1
iGMDRD30917AAG1
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CADPS

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