CHGB


Summary: This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
chromogranin BMIM:118920Ensembl:ENSG00000089199HGNC:HGNC:1930PA2646220p12.3

GO terms in CHGB


Term TypeEvidence TypeGO Term IDGO Des.
CCIEAGO:0005576extracellular region
CCIBAGO:0005615extracellular space
CCTASGO:0005788endoplasmic reticulum lumen
CCIBAGO:0030141secretory granule
CCIEAGO:0030141secretory granule
BPIEAGO:0010469regulation of signaling receptor activity
BPTASGO:0043687post-translational protein modification
BPTASGO:0044267cellular protein metabolic process
MFTASGO:0005179hormone activity
MFIPIGO:0005515protein binding

Gene expression in normal tissue: CHGB

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CHGB


DatabasePathway IDPathway Des.
reactomeR-HSA-381426Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
reactomeR-HSA-392499Metabolism of proteins
reactomeR-HSA-597592Post-translational protein modification
reactomeR-HSA-8957275Post-translational protein phosphorylation

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD131Erlotinib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CHGB

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