CHGB
Summary: This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
chromogranin B | MIM:118920 | Ensembl:ENSG00000089199 | HGNC:HGNC:1930 | PA26462 | 20p12.3 |
GO terms in CHGB
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | IEA | GO:0005576 | extracellular region |
CC | IBA | GO:0005615 | extracellular space |
CC | TAS | GO:0005788 | endoplasmic reticulum lumen |
CC | IBA | GO:0030141 | secretory granule |
CC | IEA | GO:0030141 | secretory granule |
BP | IEA | GO:0010469 | regulation of signaling receptor activity |
BP | TAS | GO:0043687 | post-translational protein modification |
BP | TAS | GO:0044267 | cellular protein metabolic process |
MF | TAS | GO:0005179 | hormone activity |
MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: CHGB
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CHGB
Database | Pathway ID | Pathway Des. |
---|---|---|
reactome | R-HSA-381426 | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
reactome | R-HSA-392499 | Metabolism of proteins |
reactome | R-HSA-597592 | Post-translational protein modification |
reactome | R-HSA-8957275 | Post-translational protein phosphorylation |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CHGB