DHX15
Summary: The protein encoded by this gene is a putative ATP-dependent RNA helicase implicated in pre-mRNA splicing. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| DEAH-box helicase 15 | MIM:603403 | Ensembl:ENSG00000109606 | HGNC:HGNC:2738 | PA27204 | 4p15.2 |
GO terms in DHX15
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0003723 | RNA binding |
| MF | TAS | GO:0003724 | RNA helicase activity |
| MF | IDA | GO:0003725 | double-stranded RNA binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IBA | GO:0034459 | ATP-dependent 3'-5' RNA helicase activity |
| BP | TAS | GO:0000398 | mRNA splicing, via spliceosome |
| BP | TAS | GO:0006397 | mRNA processing |
| BP | IC | GO:0008380 | RNA splicing |
| BP | IEA | GO:0009636 | response to toxic substance |
| BP | IEA | GO:0043279 | response to alkaloid |
| CC | IBA | GO:0005622 | intracellular |
| CC | TAS | GO:0005634 | nucleus |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IBA | GO:0005681 | spliceosomal complex |
| CC | IDA | GO:0005689 | U12-type spliceosomal complex |
| CC | IEA | GO:0005730 | nucleolus |
| CC | IDA | GO:0016607 | nuclear speck |
| CC | IDA | GO:0071008 | U2-type post-mRNA release spliceosomal complex |
Gene expression in normal tissue: DHX15
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DHX15
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-72163 | mRNA Splicing - Major Pathway |
| reactome | R-HSA-72172 | mRNA Splicing |
| reactome | R-HSA-72203 | Processing of Capped Intron-Containing Pre-mRNA |
| reactome | R-HSA-8953854 | Metabolism of RNA |
| kegg | hsa03040 | Spliceosome - Homo sapiens (human) |
| wikipathways | WP2002 | miR-targeted genes in epithelium - TarBase |
| wikipathways | WP2004 | miR-targeted genes in lymphocytes - TarBase |
| wikipathways | WP2005 | miR-targeted genes in muscle cell - TarBase |
| wikipathways | WP411 | mRNA Processing |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in DHX15
CLASSFICATION
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