DHX32


Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the full length nature of one of the variants has not been defined. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
DEAH-box helicase 32 (putative)MIM:607960Ensembl:ENSG00000089876HGNC:HGNC:16717PA2721910q26.2

GO terms in DHX32


Term TypeEvidence TypeGO Term IDGO Des.
CCIBAGO:0005622intracellular
CCIBAGO:0005681spliceosomal complex
CCIEAGO:0005739mitochondrion
MFIPIGO:0005515protein binding
MFIEAGO:0005524ATP binding
MFIBAGO:0034459ATP-dependent 3'-5' RNA helicase activity

Gene expression in normal tissue: DHX32

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in DHX32


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD399Selumetinib1
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in DHX32

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