DOK6


Summary: DOK6 is a member of the DOK (see DOK1; MIM 602919) family of intracellular adaptors that play a role in the RET (MIM 164761) signaling cascade (Crowder et al., 2004 [PubMed 15286081]).[supplied by OMIM, Mar 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
docking protein 6MIM:611402Ensembl:ENSG00000206052HGNC:HGNC:28301PA13486699518q22.2

GO terms in DOK6


Term TypeEvidence TypeGO Term IDGO Des.
MFIPIGO:0005515protein binding
CCTASGO:0005829cytosol
BPTASGO:0007411axon guidance

Gene expression in normal tissue: DOK6

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in DOK6


DatabasePathway IDPathway Des.
reactomeR-HSA-1266738Developmental Biology
reactomeR-HSA-422475Axon guidance
reactomeR-HSA-8853659RET signaling
pidret_pathwaySignaling events regulated by Ret tyrosine kinase

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD399Selumetinib1
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in DOK6

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