ERC2


Summary: This gene encodes a protein that belongs to the Rab3-interacting molecule (RIM)-binding protein family. Members of this protein family form part of the cytomatrix at the active zone (CAZ) complex and function as regulators of neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
ELKS/RAB6-interacting/CAST family member 2MIM:617250Ensembl:ENSG00000187672HGNC:HGNC:31922PA1623852493p14.3

GO terms in ERC2


Term TypeEvidence TypeGO Term IDGO Des.
CCIEAGO:0005737cytoplasm
CCIEAGO:0005856cytoskeleton
CCIEAGO:0030054cell junction
CCISSGO:0030426growth cone
CCISSGO:0042734presynaptic membrane
CCTASGO:0048786presynaptic active zone
MFIPIGO:0005515protein binding

Gene expression in normal tissue: ERC2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ERC2


DatabasePathway IDPathway Des.
wikipathwaysWP410Exercise-induced Circadian Regulation

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012
iGMDRD409Saracatinib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ERC2

​​​​