ESCO1


Summary: ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005 [PubMed 15958495]).[supplied by OMIM, Mar 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
establishment of sister chromatid cohesion N-acetyltransferase 1MIM:609674Ensembl:ENSG00000141446HGNC:HGNC:24645PA13492421518q11.2

GO terms in ESCO1


Term TypeEvidence TypeGO Term IDGO Des.
MFIDAGO:0008080N-acetyltransferase activity
MFTASGO:0008080N-acetyltransferase activity
MFIDAGO:0008270zinc ion binding
MFIDAGO:0016407acetyltransferase activity
MFIDAGO:0061733peptide-lysine-N-acetyltransferase activity
BPIBAGO:0006275regulation of DNA replication
BPIMPGO:0006275regulation of DNA replication
BPIBAGO:0007062sister chromatid cohesion
BPIEAGO:0007062sister chromatid cohesion
BPIDAGO:0018394peptidyl-lysine acetylation
BPIBAGO:0034421post-translational protein acetylation
BPIMPGO:0034421post-translational protein acetylation
CCIDAGO:0000785chromatin
CCTASGO:0005654nucleoplasm
CCIDAGO:0005694chromosome

Gene expression in normal tissue: ESCO1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ESCO1


DatabasePathway IDPathway Des.
reactomeR-HSA-1640170Cell Cycle
reactomeR-HSA-2468052Establishment of Sister Chromatid Cohesion
reactomeR-HSA-69242S Phase
reactomeR-HSA-69278Cell Cycle, Mitotic

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD491TAE-6841

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ESCO1

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