ESCO1
Summary: ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005 [PubMed 15958495]).[supplied by OMIM, Mar 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| establishment of sister chromatid cohesion N-acetyltransferase 1 | MIM:609674 | Ensembl:ENSG00000141446 | HGNC:HGNC:24645 | PA134924215 | 18q11.2 |
GO terms in ESCO1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0008080 | N-acetyltransferase activity |
| MF | TAS | GO:0008080 | N-acetyltransferase activity |
| MF | IDA | GO:0008270 | zinc ion binding |
| MF | IDA | GO:0016407 | acetyltransferase activity |
| MF | IDA | GO:0061733 | peptide-lysine-N-acetyltransferase activity |
| BP | IBA | GO:0006275 | regulation of DNA replication |
| BP | IMP | GO:0006275 | regulation of DNA replication |
| BP | IBA | GO:0007062 | sister chromatid cohesion |
| BP | IEA | GO:0007062 | sister chromatid cohesion |
| BP | IDA | GO:0018394 | peptidyl-lysine acetylation |
| BP | IBA | GO:0034421 | post-translational protein acetylation |
| BP | IMP | GO:0034421 | post-translational protein acetylation |
| CC | IDA | GO:0000785 | chromatin |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005694 | chromosome |
Gene expression in normal tissue: ESCO1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ESCO1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1640170 | Cell Cycle |
| reactome | R-HSA-2468052 | Establishment of Sister Chromatid Cohesion |
| reactome | R-HSA-69242 | S Phase |
| reactome | R-HSA-69278 | Cell Cycle, Mitotic |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ESCO1
CLASSFICATION
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