GCNT3


Summary: This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.[provided by RefSeq, Apr 2009].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
glucosaminyl (N-acetyl) transferase 3, mucin typeMIM:606836Ensembl:ENSG00000140297HGNC:HGNC:4205PA2862015q22.2

GO terms in GCNT3


Term TypeEvidence TypeGO Term IDGO Des.
MFTASGO:0003829beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity
MFIEAGO:0008109N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity
MFIEAGO:0047225acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity
CCTASGO:0000139Golgi membrane
CCTASGO:0016020membrane
CCIEAGO:0016021integral component of membrane
CCHDAGO:0070062extracellular exosome
BPIEAGO:0002426immunoglobulin production in mucosal tissue
BPNASGO:0005975carbohydrate metabolic process
BPTASGO:0006493protein O-linked glycosylation
BPTASGO:0016266O-glycan processing
BPIEAGO:0048729tissue morphogenesis
BPIEAGO:0050892intestinal absorption
BPIEAGO:0060993kidney morphogenesis

Gene expression in normal tissue: GCNT3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in GCNT3


DatabasePathway IDPathway Des.
kegghsa00512Mucin type O-glycan biosynthesis - Homo sapiens (human)
humancycPWY-7433mucin core 1 and core 2 O-glycosylation
humancycPWY-7434terminal O-glycans residues modification
reactomeR-HSA-392499Metabolism of proteins
reactomeR-HSA-5173105O-linked glycosylation
reactomeR-HSA-597592Post-translational protein modification
reactomeR-HSA-913709O-linked glycosylation of mucins

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD131Erlotinib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GCNT3

​​​​