HSD17B2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| hydroxysteroid 17-beta dehydrogenase 2 | MIM:109685 | Ensembl:ENSG00000086696 | HGNC:HGNC:5211 | PA29479 | 16q23.3 |
GO terms in HSD17B2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0005789 | endoplasmic reticulum membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| BP | IEA | GO:0001701 | in utero embryonic development |
| BP | IEA | GO:0001890 | placenta development |
| BP | TAS | GO:0006703 | estrogen biosynthetic process |
| BP | IDA | GO:0032526 | response to retinoic acid |
| BP | IEA | GO:0055114 | oxidation-reduction process |
| MF | IDA | GO:0004303 | estradiol 17-beta-dehydrogenase activity |
| MF | TAS | GO:0004303 | estradiol 17-beta-dehydrogenase activity |
| MF | TAS | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity |
| MF | IDA | GO:0047035 | testosterone dehydrogenase (NAD+) activity |
Gene expression in normal tissue: HSD17B2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HSD17B2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa00140 | Steroid hormone biosynthesis - Homo sapiens (human) |
| kegg | hsa04913 | Ovarian steroidogenesis - Homo sapiens (human) |
| wikipathways | WP2263 | Androgen Receptor Network in Prostate Cancer |
| wikipathways | WP2877 | Vitamin D Receptor Pathway |
| wikipathways | WP496 | Steroid Biosynthesis |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-193144 | Estrogen biosynthesis |
| reactome | R-HSA-196071 | Metabolism of steroid hormones |
| reactome | R-HSA-556833 | Metabolism of lipids |
| reactome | R-HSA-8957322 | Metabolism of steroids |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in HSD17B2
CLASSFICATION
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