HSPB7
Summary: This gene encodes a small heat shock family B member that can heterodimerize with similar heat shock proteins. Defects in this gene are associated with advanced heart failure. In addition, the encoded protein may be a tumor suppressor in the p53 pathway, with defects in this gene being associated with renal cell carcinoma. [provided by RefSeq, Mar 2017].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:610692 Ensembl IDEnsembl:ENSG00000173641 HGNC IDHGNC:HGNC:5249 PHARMGKB IDPA29514 Map Location1p36.13 |
GO terms in HSPB7
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IPI | GO:0005515 | protein binding |
MF | TAS | GO:0008022 | protein C-terminus binding |
MF | IEA | GO:0031005 | filamin binding |
BP | TAS | GO:0006986 | response to unfolded protein |
BP | IEA | GO:0007507 | heart development |
BP | TAS | GO:0008016 | regulation of heart contraction |
Gene expression in normal tissue: HSPB7
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HSPB7
Loading, please wait...
Database | Pathway ID | Pathway Des. |
---|---|---|
wikipathways | WP2895 | Differentiation of white and brown adipocyte |
Showing 1 to 1 of 1 rows
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD456 | Crizotinib | 1 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in HSPB7
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
---|---|---|---|---|---|---|---|---|
No matching records found |