Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008].

mitochondrial ribosomal protein L38MIM:611844Ensembl:ENSG00000204316HGNC:HGNC:14033PA3096917q25.1

GO terms in MRPL38

Term TypeEvidence TypeGO Term IDGO Des.
BPTASGO:0070125mitochondrial translational elongation
BPTASGO:0070126mitochondrial translational termination
CCTASGO:0005743mitochondrial inner membrane
CCIBAGO:0005762mitochondrial large ribosomal subunit
CCIDAGO:0005762mitochondrial large ribosomal subunit

Gene expression in normal tissue: MRPL38

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in MRPL38

DatabasePathway IDPathway Des.
reactomeR-HSA-392499Metabolism of proteins
reactomeR-HSA-392499Metabolism of proteins
reactomeR-HSA-5368286Mitochondrial translation initiation
reactomeR-HSA-5368287Mitochondrial translation
reactomeR-HSA-5368287Mitochondrial translation
reactomeR-HSA-5389840Mitochondrial translation elongation
reactomeR-HSA-5389840Mitochondrial translation elongation
reactomeR-HSA-5419276Mitochondrial translation termination

Gene-Drug: Aster Plot

Drug IDDrug NameModel Num.

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MRPL38