Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].

olfactory receptor family 6 subfamily F member 1Ensembl:ENSG00000169214HGNC:HGNC:15027PA325851q44

GO terms in OR6F1

Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0007186G-protein coupled receptor signaling pathway
BPIEAGO:0050911detection of chemical stimulus involved in sensory perception of smell
CCTASGO:0005886plasma membrane
CCIEAGO:0016021integral component of membrane
MFIEAGO:0004930G-protein coupled receptor activity
MFIBAGO:0004984olfactory receptor activity
MFIEAGO:0004984olfactory receptor activity

Gene expression in normal tissue: OR6F1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in OR6F1

DatabasePathway IDPathway Des.
wikipathwaysWP3608Olfactory receptor activity
kegghsa04740Olfactory transduction - Homo sapiens (human)
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-372790Signaling by GPCR
reactomeR-HSA-381753Olfactory Signaling Pathway
reactomeR-HSA-388396GPCR downstream signalling
reactomeR-HSA-418555G alpha (s) signalling events

Gene-Drug: Aster Plot

Drug IDDrug NameModel Num.

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in OR6F1