P2RY8
Summary: The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| P2Y receptor family member 8 | MIM:300525 | Ensembl:ENSG00000182162 | HGNC:HGNC:15524 | PA32873 | Xp22.33 and Yp11.2 |
GO terms in P2RY8
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005887 | integral component of plasma membrane |
| BP | IBA | GO:0035025 | positive regulation of Rho protein signal transduction |
| BP | IEA | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway |
| BP | IBA | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway |
| MF | IBA | GO:0004930 | G-protein coupled receptor activity |
| MF | IEA | GO:0045028 | G-protein coupled purinergic nucleotide receptor activity |
Gene expression in normal tissue: P2RY8
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in P2RY8
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in P2RY8
CLASSFICATION
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