P2RY8


Summary: The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
P2Y receptor family member 8MIM:300525Ensembl:ENSG00000182162HGNC:HGNC:15524PA32873Xp22.33 and Yp11.2

GO terms in P2RY8


Term TypeEvidence TypeGO Term IDGO Des.
CCIBAGO:0005887integral component of plasma membrane
BPIBAGO:0035025positive regulation of Rho protein signal transduction
BPIEAGO:0035589G-protein coupled purinergic nucleotide receptor signaling pathway
BPIBAGO:0051482positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
MFIBAGO:0004930G-protein coupled receptor activity
MFIEAGO:0045028G-protein coupled purinergic nucleotide receptor activity

Gene expression in normal tissue: P2RY8

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in P2RY8


DatabasePathway IDPathway Des.
kegghsa04080Neuroactive ligand-receptor interaction - Homo sapiens (human)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011
iGMDRD399Selumetinib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in P2RY8

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