PCDH18


Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
protocadherin 18MIM:608287Ensembl:ENSG00000189184HGNC:HGNC:14268PA330024q28.3

GO terms in PCDH18


Term TypeEvidence TypeGO Term IDGO Des.
CCIBAGO:0005887integral component of plasma membrane
BPIBAGO:0007155cell adhesion
BPIEAGO:0007156homophilic cell adhesion via plasma membrane adhesion molecules
BPIBAGO:0007267cell-cell signaling
BPISSGO:0007420brain development
MFIEAGO:0005509calcium ion binding

Gene expression in normal tissue: PCDH18

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PCDH18


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD387CHIR-990211
iGMDRD200STF622471
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PCDH18

​​​​