PGBD5
Summary: The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. [provided by RefSeq, May 2010].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| piggyBac transposable element derived 5 | MIM:616791 | Ensembl:ENSG00000177614 | HGNC:HGNC:19405 | PA134905621 | 1q42.13 |
GO terms in PGBD5
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0032196 | transposition |
| BP | IEA | GO:0090305 | nucleic acid phosphodiester bond hydrolysis |
| CC | IEA | GO:0005634 | nucleus |
| MF | IEA | GO:0004519 | endonuclease activity |
Gene expression in normal tissue: PGBD5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PGBD5
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP4018 | Pathways in clear cell renal cell carcinoma |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD284 | Palbociclib | 1 |
| iGMDRD309 | 17AAG | 1 |
| iGMDRD68 | Paclitaxel | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PGBD5
CLASSFICATION
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