PHLDB2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| pleckstrin homology like domain family B member 2 | MIM:610298 | Ensembl:ENSG00000144824 | HGNC:HGNC:29573 | PA134884060 | 3q13.2 |
GO terms in PHLDB2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005829 | cytosol |
| CC | IDA | GO:0005886 | plasma membrane |
| CC | IDA | GO:0005925 | focal adhesion |
| CC | IDA | GO:0031252 | cell leading edge |
| CC | IDA | GO:0045111 | intermediate filament cytoskeleton |
| CC | IDA | GO:0045180 | basal cortex |
| BP | IMP | GO:0000226 | microtubule cytoskeleton organization |
| BP | IMP | GO:0010470 | regulation of gastrulation |
| BP | IMP | GO:0010717 | regulation of epithelial to mesenchymal transition |
| BP | IMP | GO:0045184 | establishment of protein localization |
| BP | IMP | GO:0051497 | negative regulation of stress fiber assembly |
| BP | IMP | GO:0051895 | negative regulation of focal adhesion assembly |
| BP | IGI | GO:0070507 | regulation of microtubule cytoskeleton organization |
| BP | IMP | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells |
| BP | IGI | GO:1904261 | positive regulation of basement membrane assembly involved in embryonic body morphogenesis |
| BP | IMP | GO:1904261 | positive regulation of basement membrane assembly involved in embryonic body morphogenesis |
| MF | IPI | GO:0005515 | protein binding |
| MF | HDA | GO:0045296 | cadherin binding |
Gene expression in normal tissue: PHLDB2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PHLDB2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2002 | miR-targeted genes in epithelium - TarBase |
| wikipathways | WP2005 | miR-targeted genes in muscle cell - TarBase |
| wikipathways | WP2038 | Regulation of Microtubule Cytoskeleton |
| netpath | Pathway_EGFR1 | EGFR1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PHLDB2
CLASSFICATION
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