RGS7
Summary:
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
regulator of G protein signaling 7 | MIM:602517 | Ensembl:ENSG00000182901 | HGNC:HGNC:10003 | PA34378 | 1q43|1q23.1 |
GO terms in RGS7
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IDA | GO:0005096 | GTPase activator activity |
MF | IPI | GO:0031681 | G-protein beta-subunit binding |
CC | IDA | GO:0005829 | cytosol |
CC | TAS | GO:0005886 | plasma membrane |
BP | TAS | GO:0006457 | protein folding |
BP | IEA | GO:0007186 | G-protein coupled receptor signaling pathway |
BP | IEA | GO:0009968 | negative regulation of signal transduction |
BP | IEA | GO:0035556 | intracellular signal transduction |
BP | IDA | GO:0043547 | positive regulation of GTPase activity |
Gene expression in normal tissue: RGS7
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RGS7
Database | Pathway ID | Pathway Des. |
---|---|---|
wikipathways | WP289 | Myometrial Relaxation and Contraction Pathways |
wikipathways | WP536 | Calcium Regulation in the Cardiac Cell |
reactome | R-HSA-162582 | Signal Transduction |
reactome | R-HSA-372790 | Signaling by GPCR |
reactome | R-HSA-388396 | GPCR downstream signalling |
reactome | R-HSA-390466 | Chaperonin-mediated protein folding |
reactome | R-HSA-391251 | Protein folding |
reactome | R-HSA-392499 | Metabolism of proteins |
reactome | R-HSA-418594 | G alpha (i) signalling events |
reactome | R-HSA-6814122 | Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RGS7