SLC6A6


Summary: This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013].

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GO terms in SLC6A6


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0005215 transporter activity
MF IEA GO:0005328 neurotransmitter:sodium symporter activity
MF IBA GO:0005369 taurine:sodium symporter activity
MF TAS GO:0015171 amino acid transmembrane transporter activity
BP TAS GO:0006520 cellular amino acid metabolic process
BP IEA GO:0006836 neurotransmitter transport
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Gene expression in normal tissue: SLC6A6

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SLC6A6


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Database
Pathway ID
Pathway Des.
wikipathways WP2882 Nuclear Receptors Meta-Pathway
wikipathways WP2884 NRF2 pathway
reactome R-HSA-352230 Amino acid transport across the plasma membrane
reactome R-HSA-382551 Transport of small molecules
reactome R-HSA-425366 Transport of bile salts and organic acids, metal ions and amine compounds
reactome R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD409 Saracatinib 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SLC6A6

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