SLFN11
Summary:
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
schlafen family member 11 | MIM:614953 | Ensembl:ENSG00000172716 | HGNC:HGNC:26633 | PA144596358 | 17q12 |
Gene Categories:
TUMOR SUPPRESSORGO terms in SLFN11
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IBA | GO:0000049 | tRNA binding |
MF | IDA | GO:0000049 | tRNA binding |
MF | IEA | GO:0004386 | helicase activity |
MF | IPI | GO:0005515 | protein binding |
MF | IEA | GO:0005524 | ATP binding |
MF | IDA | GO:0016887 | ATPase activity |
CC | IDA | GO:0005634 | nucleus |
CC | IDA | GO:0005654 | nucleoplasm |
CC | IDA | GO:0005829 | cytosol |
CC | IDA | GO:0016235 | aggresome |
CC | IDA | GO:0090734 | site of DNA damage |
BP | IDA | GO:0006974 | cellular response to DNA damage stimulus |
BP | IDA | GO:0008156 | negative regulation of DNA replication |
BP | IDA | GO:0010942 | positive regulation of cell death |
BP | IDA | GO:0043111 | replication fork arrest |
BP | IBA | GO:0051607 | defense response to virus |
BP | IMP | GO:0051607 | defense response to virus |
BP | IMP | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle |
Gene expression in normal tissue: SLFN11
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SLFN11
Database | Pathway ID | Pathway Des. |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SLFN11