SPECC1


Summary: The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
sperm antigen with calponin homology and coiled-coil domains 1MIM:608793Ensembl:ENSG00000128487HGNC:HGNC:30615PA16471871217p11.2

GO terms in SPECC1


Term TypeEvidence TypeGO Term IDGO Des.
BPIBAGO:0030036actin cytoskeleton organization
CCIEAGO:0005634nucleus
CCIBAGO:0005815microtubule organizing center
CCIEAGO:0016020membrane
CCIBAGO:0031941filamentous actin

Gene expression in normal tissue: SPECC1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SPECC1


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD748PHA-6657521

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SPECC1

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