TMBIM1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| transmembrane BAX inhibitor motif containing 1 | MIM:610364 | Ensembl:ENSG00000135926 | HGNC:HGNC:23410 | PA142670804 | 2q35 |
GO terms in TMBIM1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0005123 | death receptor binding |
| CC | HDA | GO:0005765 | lysosomal membrane |
| CC | IDA | GO:0005765 | lysosomal membrane |
| CC | IDA | GO:0005794 | Golgi apparatus |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IDA | GO:0010008 | endosome membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | TAS | GO:0035579 | specific granule membrane |
| CC | IDA | GO:0043231 | intracellular membrane-bounded organelle |
| CC | HDA | GO:0070062 | extracellular exosome |
| BP | ISS | GO:0043086 | negative regulation of catalytic activity |
| BP | TAS | GO:0043312 | neutrophil degranulation |
| BP | IMP | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors |
| BP | IMP | GO:1902045 | negative regulation of Fas signaling pathway |
| BP | IMP | GO:1903077 | negative regulation of protein localization to plasma membrane |
| BP | ISS | GO:2000504 | positive regulation of blood vessel remodeling |
Gene expression in normal tissue: TMBIM1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TMBIM1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-168249 | Innate Immune System |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-6798695 | Neutrophil degranulation |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TMBIM1
CLASSFICATION
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