TPGS2


Summary: This gene encodes a protein that is a component of the neuronal polyglutamylase complex, which plays a role in post-translational addition of glutamate residues to C-terminal tubulin tails. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
tubulin polyglutamylase complex subunit 2Ensembl:ENSG00000134779HGNC:HGNC:24561PA12839463718q12.2

GO terms in TPGS2


Term TypeEvidence TypeGO Term IDGO Des.
CCIEAGO:0005737cytoplasm
CCIEAGO:0005874microtubule

Gene expression in normal tissue: TPGS2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TPGS2


DatabasePathway IDPathway Des.
reactomeR-HSA-392499Metabolism of proteins
reactomeR-HSA-597592Post-translational protein modification
reactomeR-HSA-8955332Carboxyterminal post-translational modifications of tubulin

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD536PLX-47201

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TPGS2

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