UGT2B11


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
UDP glucuronosyltransferase family 2 member B11MIM:603064Ensembl:ENSG00000213759HGNC:HGNC:12545PA371874q13.2

Gene Categories:

DRUGGABLE GENOME

GO terms in UGT2B11


Term TypeEvidence TypeGO Term IDGO Des.
BPTASGO:0006805xenobiotic metabolic process
BPIDAGO:0008210estrogen metabolic process
BPIDAGO:0052697xenobiotic glucuronidation
CCIEAGO:0005789endoplasmic reticulum membrane
CCIEAGO:0016021integral component of membrane
CCIEAGO:0031090organelle membrane
CCIBAGO:0043231intracellular membrane-bounded organelle
MFIBAGO:0008194UDP-glycosyltransferase activity
MFIDAGO:0015020glucuronosyltransferase activity

Gene expression in normal tissue: UGT2B11

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in UGT2B11


DatabasePathway IDPathway Des.
reactomeR-HSA-1430728Metabolism
reactomeR-HSA-156580Phase II - Conjugation of compounds
reactomeR-HSA-156588Glucuronidation
reactomeR-HSA-211859Biological oxidations
humancycPWY-6261thyroid hormone metabolism II (via conjugation and/or degradation)
humancycPWY-6313serotonin degradation
humancycPWY-6398melatonin degradation I
humancycPWY-6402superpathway of melatonin degradation
humancycPWY66-201nicotine degradation IV
humancycPWY66-221nicotine degradation III
humancycPWY66-401superpathway of tryptophan utilization
kegghsa00040Pentose and glucuronate interconversions - Homo sapiens (human)
kegghsa00053Ascorbate and aldarate metabolism - Homo sapiens (human)
kegghsa00140Steroid hormone biosynthesis - Homo sapiens (human)
kegghsa00830Retinol metabolism - Homo sapiens (human)
kegghsa00860Porphyrin and chlorophyll metabolism - Homo sapiens (human)
kegghsa00980Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human)
kegghsa00982Drug metabolism - cytochrome P450 - Homo sapiens (human)
kegghsa00983Drug metabolism - other enzymes - Homo sapiens (human)
kegghsa05204Chemical carcinogenesis - Homo sapiens (human)
smpdbSMP00024Porphyrin Metabolism
smpdbSMP00058Starch and Sucrose Metabolism
smpdbSMP00068Androgen and Estrogen Metabolism
smpdbSMP00342Hereditary Coproporphyria (HCP)
smpdbSMP00344Acute Intermittent Porphyria
smpdbSMP00345Congenital Erythropoietic Porphyria (CEP) or Gunther Disease
smpdbSMP00346Porphyria Variegata (PV)
smpdbSMP0035617-Beta Hydroxysteroid Dehydrogenase III Deficiency
smpdbSMP00552Glycogen synthetase deficiency
smpdbSMP00553Glycogenosis, Type III. Cori disease, Debrancher glycogenosis
smpdbSMP00554Glycogenosis, Type IV. Amylopectinosis, Anderson disease
smpdbSMP00555Glycogenosis, Type VI. Hers disease
smpdbSMP00556Mucopolysaccharidosis VI. Sly syndrome
smpdbSMP00557Sucrase-isomaltase deficiency
smpdbSMP00565Aromatase deficiency
wikipathwaysWP698Glucuronidation
wikipathwaysWP702Metapathway biotransformation Phase I and II

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD491TAE-6841

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in UGT2B11

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