iGMDRD1018


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Standard Name
Drug Status
Standard NameTL-1-85
Drug StatusAlone

Drug Targets:

TAK

Drug Pathways:

Other, kinases

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 3LYMPtissue: LYMP cancer: LYMPH model num: 0LYMPHtissue: LYMPH cancer: Diffuse Large B-Cell Lymphoma (DLBCL) model num: 1BONtissue: BON cancer: BONE model num: 0BONEtissue: BONE cancer: Acute Myeloid Leukemia (AML) model num: 1

Drug-gene pathway enrichments

6reactome: Signal Transduction4reactome: p38MAPK events4reactome: Signaling by Receptor Tyrosine Kinases4reactome: Signaling by NTRK1 (TRKA)4reactome: Signalling to RAS4reactome: Signaling by NTRKs4reactome: Signaling by ERBB24reactome: Developmental Biology4reactome: Signalling to ERKs4reactome: GRB2 events in ERBB2 signaling

Drug-gene GO enrichments

4CC: nucleoplasm3MF: protein binding3MF: transcription coactivator activity3BP: stimulatory C-type lectin receptor signaling pathway3CC: nucleus3BP: positive regulation of transcription by RNA polymerase II2BP: positive regulation of transcription, DNA-templated2CC: nuclear chromatin2MF: GTP binding2MF: protein-containing complex binding

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3845 KRAS 1
55252 ASXL2 1
1387 CREBBP 1
4893 NRAS 2
Showing 1 to 4 of 4 rows

Gene in drug-gene network: Network Plot

Models in TL-1-85

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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