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TL-1-85
iGMDRD1018
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Standard Name
Drug Status
Standard Name
TL-1-85
Drug Status
Alone
Drug Targets:
TAK
Drug Pathways:
Other, kinases
Drug-model tissue-cancer distribution: Bubble Plot
undefine
tissue: undefine cancer: undefined model num: 0
undefined
tissue: undefined cancer: PANCAN model num: 3
LYMP
tissue: LYMP cancer: LYMPH model num: 0
LYMPH
tissue: LYMPH cancer: Diffuse Large B-Cell Lymphoma (DLBCL) model num: 1
BON
tissue: BON cancer: BONE model num: 0
BONE
tissue: BONE cancer: Acute Myeloid Leukemia (AML) model num: 1
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Drug-gene pathway enrichments
6
reactome: Signal Transduction
4
reactome: p38MAPK events
4
reactome: Signaling by Receptor Tyrosine Kinases
4
reactome: Signaling by NTRK1 (TRKA)
4
reactome: Signalling to RAS
4
reactome: Signaling by NTRKs
4
reactome: Signaling by ERBB2
4
reactome: Developmental Biology
4
reactome: Signalling to ERKs
4
reactome: GRB2 events in ERBB2 signaling
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Drug-gene GO enrichments
4
CC: nucleoplasm
3
MF: protein binding
3
MF: transcription coactivator activity
3
BP: stimulatory C-type lectin receptor signaling pathway
3
CC: nucleus
3
BP: positive regulation of transcription by RNA polymerase II
2
BP: positive regulation of transcription, DNA-templated
2
CC: nuclear chromatin
2
MF: GTP binding
2
MF: protein-containing complex binding
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Drug-Gene: Aster Plot
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Gene ID
Gene Name
Model Num.
3845
KRAS
1
55252
ASXL2
1
1387
CREBBP
1
4893
NRAS
2
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Gene in drug-gene network: Network Plot
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Models in TL-1-85
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found
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