iGMDRD25

Canonical SMILES: CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5

InChI: InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)

InChI Key: YOSHYTLCDANDAN-UHFFFAOYSA-N

Loading, please wait...
Standard Name
CHEMBL
Pubchem CID
KEGG Drug ID
DRUGBANK ID
Drug Status
Drug targets (TTD)
Drug Type
Standard Name138402-11-6
CHEMBLCHEMBL1513
Pubchem CID3749
KEGG Drug IDD00523
DRUGBANK IDDB01029
Drug StatusAlone
Drug targets (TTD)DAP000364
Drug TypeSmall Molecule




Drug-model tissue-cancer distribution: Bubble Plot

BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: Colorectal Adenocarcinoma (COADREAD) model num: 2

Drug-gene pathway enrichments

3reactome: Signal Transduction2kegg: T cell receptor signaling pathway - Homo sapiens (human)2kegg: B cell receptor signaling pathway - Homo sapiens (human)2kegg: Estrogen signaling pathway - Homo sapiens (human)2kegg: Th17 cell differentiation - Homo sapiens (human)2kegg: TNF signaling pathway - Homo sapiens (human)2kegg: Th1 and Th2 cell differentiation - Homo sapiens (human)2kegg: Osteoclast differentiation - Homo sapiens (human)2kegg: Toll-like receptor signaling pathway - Homo sapiens (human)2kegg: IL-17 signaling pathway - Homo sapiens (human)

Drug-gene GO enrichments

8MF: RNA polymerase II transcription factor activity, sequence-specific DNA binding6BP: positive regulation of transcription by RNA polymerase II5CC: nucleoplasm4CC: transcription factor AP-1 complex4BP: positive regulation of transcription, DNA-templated3CC: nucleus3MF: RNA polymerase II proximal promoter sequence-specific DNA binding3BP: cellular response to reactive oxygen species3MF: transcription factor binding3BP: positive regulation of pri-miRNA transcription by RNA polymerase II

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
3725 JUN 1
2353 FOS 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in 138402-11-6

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.