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iGMDRD25

Canonical SMILES: CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5

InChI: InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)

InChI Key: YOSHYTLCDANDAN-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	KEGG Drug ID	DRUGBANK ID	Drug Status	Drug targets (TTD)	Drug Type
138402-11-6	CHEMBL1513	3749	D00523	DB01029	Alone	DAP000364	Small Molecule

Drug Class:

Agents Acting on the Renin-Angiotensin System Angiotensin 2 Receptor Blocker Angiotensin II Angiotensin II Antagonists and Calcium Channel Blockers Angiotensin II Antagonists and Diuretics Angiotensin II Antagonists, Plain Angiotensin II Type 1 Receptor Blockers Angiotensin Receptor Antagonists Antihypertensive Agents Azoles Benzene Derivatives Cardiovascular Agents Cardiovascular System Cytochrome P-450 CYP2C8 Inhibitors Cytochrome P-450 CYP2C8 Inhibitors (moderate)Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Enzyme Inhibitors Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Hydrocarbons Hydrocarbons, Aromatic Hydrocarbons, Cyclic Hypotensive Agents

Drug Targets:

AGTR1 (P30556)JUN (P05412)

Drug Pathways:

Neuroactive ligand-receptor interaction Adrenergic signaling in cardiomyocytes Vascular smooth muscle contraction Renin-angiotensin system

Drug Synonyms:

Irbesartan (JP17/USAN/INN)Avapro (TN)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
3725	JUN	1
2353	FOS	1

Gene in drug-gene network: Network Plot

Models in 138402-11-6

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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.