iGMDRD30


Canonical SMILES: C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4

InChI: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2

InChI Key: CZQHHVNHHHRRDU-UHFFFAOYSA-N

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Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameLY-294002
Pubchem CID3973
DRUGBANK IDDB02656
Drug StatusAlone
Drug TypeSmall Molecule


Drug-model tissue-cancer distribution: Bubble Plot

SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: Melanoma (MEL) model num: 2BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Breast Carcinoma model num: 1

Drug-gene pathway enrichments

2wikipathways: EGF-EGFR Signaling Pathway2wikipathways: Somatroph axis (GH) and its relationship to dietary restriction and aging2wikipathways: Insulin Signaling2reactome: Intracellular signaling by second messengers2wikipathways: Senescence and Autophagy in Cancer2wikipathways: PI3K-Akt Signaling Pathway2wikipathways: Pathways in clear cell renal cell carcinoma2wikipathways: ESC Pluripotency Pathways2reactome: PTEN Regulation2wikipathways: Focal Adhesion-PI3K-Akt-mTOR-signaling pathway

Drug-gene GO enrichments

3CC: cytosol3CC: cytoplasm3CC: nucleoplasm3MF: kinase activity3MF: protein serine/threonine kinase activity3BP: negative regulation of protein phosphorylation2CC: nucleus2MF: phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity2CC: lysosome2BP: cellular response to hypoxia

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2475 MTOR 2
5728 PTEN 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in LY-294002

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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