iGMDRD343


Canonical SMILES: C1CC(CCC1CCC(=O)O)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl

InChI: InChI=1S/C21H21ClF2O4S/c22-15-2-5-17(6-3-15)29(27,28)21(18-13-16(23)4-7-19(18)24)11-9-14(10-12-21)1-8-20(25)26/h2-7,13-14H,1,8-12H2,(H,25,26)

InChI Key: XCGJIFAKUZNNOR-UHFFFAOYSA-N

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Standard Name
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameMK-0752
Pubchem CID9803430
DRUGBANK IDDB12852
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1OTHEtissue: OTHE cancer: OTHER model num: 0OTHERtissue: OTHER cancer: Cancer of Unknown Primary (CUP) model num: 4BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Invasive Breast Carcinoma (BRCA) model num: 1BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: Acute Myeloid Leukemia (AML) model num: 1BLOODtissue: BLOOD cancer: Acute Lymphoid Leukemia (ALL) model num: 1

Drug-gene pathway enrichments

3wikipathways: Notch Signaling Pathway2reactome: Activated NOTCH1 Transmits Signal to the Nucleus2reactome: Generic Transcription Pathway2reactome: Pre-NOTCH Transcription and Translation2reactome: Pre-NOTCH Expression and Processing2reactome: Signal Transduction2reactome: Signaling by NOTCH12reactome: Pre-NOTCH Processing in Golgi2reactome: RNA Polymerase II Transcription2reactome: NOTCH3 Intracellular Domain Regulates Transcription

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
4851 NOTCH1 7
7301 TYRO3 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in MK-0752

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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