iGMDRD428

Canonical SMILES: CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)O)C

InChI: InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1

InChI Key: WCWUXEGQKLTGDX-LLVKDONJSA-N

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Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameBrivanib
CHEMBLCHEMBL377300
Pubchem CID11234100
DRUGBANK IDDB11958
Drug StatusAlone
Drug TypeSmall Molecule


Drug Targets:

FLT1KDR

Drug-model tissue-cancer distribution: Bubble Plot

OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Drug-gene pathway enrichments

3wikipathways: PI3K-Akt Signaling Pathway3wikipathways: Focal Adhesion-PI3K-Akt-mTOR-signaling pathway3reactome: Translation3reactome: Signal Transduction3netpath: BCR3kegg: PI3K-Akt signaling pathway - Homo sapiens (human)3netpath: IL23reactome: Disease3reactome: Metabolism of proteins3wikipathways: Brain-Derived Neurotrophic Factor (BDNF) signaling pathway

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2309 FOXO3 1
1978 EIF4EBP1 1
6194 RPS6 1
Showing 1 to 3 of 3 rows

Gene in drug-gene network: Network Plot

Models in Brivanib

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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