iGMDRD623


Canonical SMILES: C[C@@H](CO)N1C[C@H](C)[C@H](CN(C)C(=O)Nc2cccc3ccccc23)Oc4ccc(NC(=O)NC5CCCCC5)cc4CC1=O

InChI: InChI=1S/C35H45N5O5/c1-23-20-40(24(2)22-41)33(42)19-26-18-28(37-34(43)36-27-12-5-4-6-13-27)16-17-31(26)45-32(23)21-39(3)35(44)38-30-15-9-11-25-10-7-8-14-29(25)30/h7-11,14-18,23-24,27,32,41H,4-6,12-13,19-22H2,1-3H3,(H,38,44)(H2,36,37,43)/t23-,24-,32-/m0/s1

InChI Key: ICEMUJZXENLAMO-TWVHRYOLSA-N

Loading, please wait...
Standard Name
Pubchem CID
Drug Status
Standard NameBRD-K52037352
Pubchem CID44493500
Drug StatusAlone

Drug-model tissue-cancer distribution: Bubble Plot

OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
1978 EIF4EBP1 1
7301 TYRO3 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in BRD-K52037352

Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
EXP(CMET_pY1235) protein MCLP OVARY undefined BRD.K52037352 sensitivity in vitro
EXP(4EBP1) protein MCLP undefined PANCAN BRD.K52037352 sensitivity in vitro
EXP(TYRO3) protein MCLP undefined PANCAN BRD.K52037352 sensitivity in vitro
Showing 1 to 3 of 3 rows

​​​​